The Ever Given, which blocked the Suez Canal in March, has passed back through the waterway without incident.
The Ever Given was among a convoy of vessels sailing from the Mediterranean Sea to the Red Sea, the Suez Canal Authority (SCA) said.
It had been offloading its cargo in Europe and is now en route to Asia.
The ship was refloated after a major six-day salvage operation that led to the death of one person.
The SCA said the Ever Given was escorted through the 193km canal by two tugboats and senior SCA guides.
It was one of 26 ships that travelled from north to south through the canal while 36 ships sailed in the opposite direction, the SCA added, and hailed the waterway as the “shortest and fastest navigational route linking the east with the west”.
The Ever Given, one of the world’s largest container ships, had been delivering its 18,300 containers to Rotterdam, Felixstowe and Hamburg and is now travelling to China.